Article
Donor mannose-binding lectin deficiency increases the likelihood of clinically significant infection after liver transplantation.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Feb 2009
Worthley Daniel L, Johnson Douglas F, Eisen Damon P, Dean Melinda M, Heatley Susan L, Tung John-Paul, Scott Justin, Padbury Robert T A, Harley Hugh A, Bardy Peter G, Angus Peter W, Mullighan Charles G
Abstract excerpt
BACKGROUND: Mannose-binding lectin (MBL) is an important mediator of innate immunity and is synthesized primarily by the liver. Low MBL levels are common, are due primarily to polymorphisms in the gene encoding MBL (MBL2), and are associated with an increased risk of infection, particularly when...
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