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Article

The apical targeting signal of the P2Y2 receptor is located in its first extracellular loop.

The Journal of biological chemistry - 12 Aug 2005

Qi Ai-Dong, Wolff Samuel C, Nicholas Robert A

Abstract excerpt

P2Y2 and P2Y4 receptors, which have 52% sequence identity, are both expressed at the apical membrane of Madin-Darby canine kidney cells, but the locations of their apical targeting signals are distinctly different. The targeting signal of the P2Y2 receptor is located between the N terminus and 7TM, whereas that of the P2Y4 receptor is present in its C-terminal tail. To identify the apical targeting signal in the...

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PMID: 15908695
DOI: 10.1074/jbc.M501301200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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