Article
Targeting of an apical endosomal protein to endosomes in Madin-Darby canine kidney cells requires two sorting motifs.
Traffic (Copenhagen, Denmark) - 1 Apr 2000
Gokay K E, Wilson J M
Abstract excerpt
The efficient sorting and targeting of endocytosed macromolecules is critical for epithelial function. However, the distribution of endosomal compartments in these cells remains controversial. In this study, we show that polarized Madin-Darby canine kidney (MDCK) cells target the apical endosomal protein endotubin into an apical early endosomal compartment that is distinct from the apical recycling endosomes....
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