Article
Familial gastric cancer: overview and guidelines for management.
Journal of medical genetics - 1 Dec 1999
Caldas C, Carneiro F, Lynch H T, Yokota J, Wiesner G L, Powell S M, Lewis F R, Huntsman D G, Pharoah P D, Jankowski J A, MacLeod P, Vogelsang H, Keller G, Park K G, Richards F M, Maher E R, Gayther S A, Oliveira C, Grehan N, Wight D, Seruca R, Roviello F, Ponder B A, Jackson C E
Abstract excerpt
Families with autosomal dominant inherited predisposition to gastric cancer have been described. More recently, germline E-cadherin/CDH1 mutations have been identified in hereditary diffuse gastric cancer kindred. The need to have protocols to manage and counsel these families in the clinic led a group of geneticists, gastroenterologists, surgeons, oncologists, pathologists, and molecular biologists to convene a...
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