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Article

Effects of retroviral envelope-protein cleavage upon trafficking, incorporation, and membrane fusion.

Virology - 15 Sept 2010

Apte Swapna, Sanders David Avram

Abstract excerpt

Retroviral envelope glycoproteins undergo proteolytic processing by cellular subtilisin-like proprotein convertases at a polybasic amino-acid site in order to produce the two functional subunits, SU and TM. Most previous studies have indicated that envelope-protein cleavage is required for rendering the protein competent for promoting membrane fusion and for virus infectivity. We have investigated the role of...

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Identifiers

PMID: 20591459
DOI: 10.1016/j.virol.2010.06.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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