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Article

Inefficient signalase cleavage promotes efficient nucleocapsid incorporation into budding flavivirus membranes.

Journal of virology - 1 Jan 2004

Lobigs Mario, Lee Eva

Abstract excerpt

The mechanism for efficient nucleocapsid (NC) uptake into flavivirus particles which form by budding through the membranes of the endoplasmic reticulum (ER) was investigated by using Murray Valley encephalitis virus as a model. Budding of flavivirus membranes is driven by the viral transmembrane proteins prM and E independently of NC interaction. We show that control of signalase cleavage of the...

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Identifiers

PMID: 14671099
DOI: 10.1128/jvi.78.1.178-186.2004
PMCID: PMC303399

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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