Article
Number of prostate cancer risk alleles may identify possibly 'insignificant' disease.
BJU international - 1 Dec 2010
Helfand Brian T, Loeb Stacy, Kan Donghui, Catalona William J
Abstract excerpt
OBJECTIVE: To determine whether the cumulative effects of five prostate cancer risk alleles (three single-nucleotide polymorphisms [SNPs] on chromosome 8Q24 and two SNPs on chromosome 17a) could help to identify possibly 'insignificant' disease. MATERIALS AND METHODS: We genotyped 629 men of European ancestry who underwent radical prostatectomy at our institution between 2002 and 2007. Possibly 'insignificant'...
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