Article
Genetic prostate cancer risk assessment: common variants in 9 genomic regions are associated with cumulative risk.
The Journal of urology - 1 Aug 2010
Helfand Brian T, Fought Angela J, Loeb Stacy, Meeks Joshua J, Kan Donghui, Catalona William J
Abstract excerpt
PURPOSE: Five genetic variants along chromosomes 8q24 and 17q have a cumulative association with prostate cancer risk. Our research group previously reported an association between these variants and clinicopathological characteristics. More recently 4 additional prostate cancer susceptibility variants were identified on chromosomes 2p15, 10q11, 11q13 and Xp11. We performed cumulative risk assessment...
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