Article
Association of prostate cancer risk alleles with unfavourable pathological characteristics in potential candidates for active surveillance.
BJU international - 1 Aug 2012
McGuire Barry B, Helfand Brian T, Kundu Shilajit, Hu Qiaoyan, Banks Jessica A, Cooper Phillip, Catalona William J
Abstract excerpt
OBJECTIVE: • To assess whether the carrier status of 35 risk alleles for prostate cancer (CaP) is associated with having unfavourable pathological features in the radical prostatectomy specimen in men with clinically low risk CaP who fulfil commonly accepted criteria as candidates for active surveillance. PATIENTS AND METHODS: • We studied men of European ancestry with CaP who fulfilled the commonly accepted...
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