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Article

Estimation of absolute risk for prostate cancer using genetic markers and family history.

The Prostate - 1 Oct 2009

Xu Jianfeng, Sun Jielin, Kader A Karim, Lindström Sara, Wiklund Fredrik, Hsu Fang-Chi, Johansson Jan-Erik, Zheng S Lilly, Thomas Gilles, Hayes Richard B, Kraft Peter, Hunter David J, Chanock Stephen J, Isaacs William B, Grönberg Henrik

Abstract excerpt

BACKGROUND: Multiple DNA sequence variants in the form of single-nucleotide polymorphisms (SNPs) have been found to be reproducibly associated with prostate cancer (PCa) risk. METHODS: Absolute risk for PCa among men with various numbers of inherited risk alleles and family history of PCa was estimated in a population-based case-control study in Sweden (2,893 cases and 1,781 controls), and a nested case-control...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19562736
DOI: 10.1002/pros.21002
PMCID: PMC2793526

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