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Article

Intravenous administration of azumolene to reverse malignant hyperthermia in swine.

Journal of veterinary internal medicine - 1 Jan 2000

do Carmo P L, Zapata-Sudo G, Trachez M M, Antunes F, Guimarães S E F, Debom R, Rizzi M D R, Sudo R T

Abstract excerpt

BACKGROUND: The efficacy of intravenous (IV) administration of azumolene (Az), an analogue 30-fold more soluble than dantrolene, on pigs susceptible to malignant hyperthermia (MH) is incompletely understood. OBJECTIVE: To evaluate efficacy of Az on MH crisis in pigs. ANIMALS: Eight normal (MHN) and 7 susceptible to MH (MHS) pigs (Landrace × Large White × Pietran). METHODS: Prospective, laboratory trial....

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PMID: 20584138
DOI: 10.1111/j.1939-1676.2010.0556.x

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