Article
3,4-Methylenedioxymethamphetamine induces a hyperthermic and hypermetabolic crisis in pigs with and without a genetic disposition for malignant hyperthermia.
European journal of anaesthesiology - 1 Jan 2013
Schütte Jan K, Schäfer Ute, Becker Sandra, Oldewurtel Christiane, Starosse Alexander, Singler Peter, Richard Annette, Wappler Frank, Gerbershagen Mark U
Abstract excerpt
BACKGROUND: Clinical symptoms of acute 3,4-methylenedioxymethamphetamine (MDMA) intoxication and malignant hyperthermia have many similarities. At present, however, there is contradictory evidence concerning the malignant hyperthermia trigger potency of MDMA. OBJECTIVE: This study was designed to investigate whether MDMA has malignant hyperthermia trigger potential and leads to malignant hyperthermia in pigs with...
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