Article
Malignant hyperthermia phenotype: hypotension induced by succinylcholine in susceptible swine.
Anesthesiology - 1 Jun 2000
Sigg D C, Iaizzo P A
Abstract excerpt
BACKGROUND: Succinylcholine causes immediate and severe arterial hypotension in swine with the malignant hyperthermia phenotype. The underlying mechanisms are unknown. METHODS: Malignant hyperthermia-susceptible (MHS; n = 10) and normal swine (n = 5) were anesthetized with thiopental. The following were monitored: electrocardiogram; arterial blood pressure; pulmonary artery, central venous, and left and right...
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