Article
Evaluation of greyhound susceptibility to malignant hyperthermia using halothane-succinylcholine anesthesia and caffeine-halothane muscle contractures.
Laboratory animal science - 1 Oct 1992
Cosgrove S B, Eisele P H, Martucci R W, Gronert G A
Abstract excerpt
We investigated Greyhounds because of prior reports of malignant hyperthermia (MH) episodes and because Greyhounds may express high genetic relatedness due to inbreeding for generations. Seven Greyhound and six mongrel dogs were given halothane and succinylcholine anesthesia as a challenge to trigger MH. They also underwent semitendinosus muscle biopsy for contracture study with halothane and caffeine....
Topics
- Anesthesia, Inhalation
- Animals
- Caffeine
- Disease Susceptibility
- Dog Diseases
- Dogs
- Genetic Predisposition to Disease
- Halothane
- In Vitro Techniques
- Malignant Hyperthermia
- Muscle Contraction