Article
A Nested Case-Control Study of Metabolically Defined Body Size Phenotypes and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC).
PLoS medicine - 1 Apr 2016
Murphy Neil, Cross Amanda J, Abubakar Mustapha, Jenab Mazda, Aleksandrova Krasimira, Boutron-Ruault Marie-Christine, Dossus Laure, Racine Antoine, Kühn Tilman, Katzke Verena A, Tjønneland Anne, Petersen Kristina E N, Overvad Kim, Quirós J Ramón, Jakszyn Paula, Molina-Montes Esther, Dorronsoro Miren, Huerta José-María, Barricarte Aurelio, Khaw Kay-Tee, Wareham Nick, Travis Ruth C, Trichopoulou Antonia, Lagiou Pagona, Trichopoulos Dimitrios, Masala Giovanna, Krogh Vittorio, Tumino Rosario, Vineis Paolo, Panico Salvatore, Bueno-de-Mesquita H Bas, Siersema Peter D, Peeters Petra H, Ohlsson Bodil, Ericson Ulrika, Palmqvist Richard, Nyström Hanna, Weiderpass Elisabete, Skeie Guri, Freisling Heinz, Kong So Yeon, Tsilidis Kostas, Muller David C, Riboli Elio, Gunter Marc J
Abstract excerpt
BACKGROUND: Obesity is positively associated with colorectal cancer. Recently, body size subtypes categorised by the prevalence of hyperinsulinaemia have been defined, and metabolically healthy overweight/obese individuals (without hyperinsulinaemia) have been suggested to be at lower risk of cardiovascular disease than their metabolically unhealthy (hyperinsulinaemic) overweight/obese counterparts. Whether...
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