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Article

Familial C4B deficiency and immune complex glomerulonephritis.

Clinical immunology (Orlando, Fla.) - 1 Oct 2010

Soto K, Wu Y L, Ortiz A, Aparício S R, Yu C Y

Abstract excerpt

Homozygous complement C4B deficiency is described in a Southern European young female patient with Membranoproliferative Glomerulonephritis (MPGN) type III characterized by renal biopsies with strong complement C4 and IgG deposits. Low C4 levels were independent of clinical evolution or type of immunosuppression and were found in three other family members without renal disease or infections. HLA typing revealed...

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Identifiers

PMID: 20580617
DOI: 10.1016/j.clim.2010.06.003
PMCID: PMC2941544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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