Article
The endothelial dysfunction in patients with type 2 diabetes mellitus is associated with IL-6 gene promoter polymorphism in Chinese population.
Endocrine - 1 Aug 2011
Zhang Xianfeng, Ma Lizhen, Peng Fengying, Wu Yin, Chen Yu, Yu Linying, Lei Zhikai, Zhang Chu
Abstract excerpt
The purpose of this study is to examine the effects of IL-6 gene promoter -174G/C and -572G/C polymorphism on endothelial function of Chinese T2DM and normal glucose regulation (NGR) subjects. 512 newly diagnosed T2DM patients and 483 NGR subjects were recruited and Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) was performed for the IL-6 gene promoter -174G/C and -572G/C...
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