Article
TNF-alpha polymorphisms and type 2 diabetes mellitus in Taiwanese patients.
Tissue antigens - 1 May 2003
Shiau M-Y, Wu C-Y, Huang C-N, Hu S-W, Lin S-J, Chang Y-H
Abstract excerpt
Type 2 diabetic mellitus (type 2 DM) comprises more than 95% of all Taiwanese patients with DM. Tumor necrosis factor-alpha (TNF-alpha) expression is linked with insulin resistance, and is under strong genetic control. The correlation between TNF promoter genotypes and type 2 DM is still controversial, because discrepancies among different studies exist. Ethnic differences play certain roles in these conflicting...
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