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Article

Toll-like receptor 2, 4 and 9 polymorphisms and their association with ICU-acquired infections in Central Greece.

Journal of critical care - 1 Oct 2018

Chatzi Maria, Papanikolaou John, Makris Demosthenes, Papathanasiou Ioanna, Tsezou Aspasia, Karvouniaris Marios, Zakynthinos Epaminondas

Abstract excerpt

PURPOSE: To test the potential of four common Toll-like receptor (TLR) polymorphisms to predispose to specific intensive care unit (ICU)-acquired infections and affect outcomes in a Greek ICU. MATERIALS AND METHODS: The incidence of TLR2-Arg753Gln, TLR4-Asp299Gly, TLR4-Thr399Ile and TLR9-T1237C polymorphisms, and their association with ICU-acquired infections and patients' clinical outcomes were prospectively...

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Identifiers

PMID: 29860039
DOI: 10.1016/j.jcrc.2018.05.012

Genes

TLR4
TLR9
TLR2

Variants

Provenance

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