Article
No associations established between single nucleotide polymorphisms in human Toll-like receptor 2 and Toll-interacting protein and Staphylococcus aureus bloodstream infections.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Oct 2017
Smeland Tom Eirik, Müller Fredrik, Blomfeldt Anita, Stavem Knut, Aamot Hege Vangstein
Abstract excerpt
Staphylococcus aureus bloodstream infections (SABSI) are associated with high morbidity and mortality. The Toll-like receptor 2 (TLR2) and Toll-interacting protein (TOLLIP) are important in recognition and regulation of human innate immunity response to S. aureus. Single nucleotide polymorphisms (SNPs) in the TLR2 and TOLLIP encoding genes have been associated with disease, including BSI. The aim of this study...
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