Article
Polymorphisms IL10-819 and TLR-2 are potentially associated with sepsis in Brazilian patients.
Memorias do Instituto Oswaldo Cruz - 1 Aug 2010
Carregaro Fernanda, Carta Adriana, Cordeiro José Antônio, Lobo Suzana M, Silva Eloiza H Tajara da, Leopoldino Andréia M
Abstract excerpt
Genetic variation in immune response is probably involved in the progression of sepsis and mortality in septic patients. However, findings in the literature are sometimes conflicting or their significance is uncertain. Thus, we investigated the possible association between 12 polymorphisms located in the interleukin-6 (IL6), IL10, TLR-2, Toll-like receptor-4 (TLR-4), tumor necrosis factor-α and tumor necrosis...
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