Article
Universal probe-based SNP genotyping with visual readout: a robust and versatile method.
Nanoscale - 3 Aug 2023
Wang Zhongzhong, Zhang Zhang, Luo Wang, Wang Luojia, Han Xiaole, Zhao Rong, Liu Xin, Zhang Jianhong, Yu Wen, Li Junjie, Yang Yujun, Zuo Chen, Xie Guoming
Abstract excerpt
Detection of single nucleotide polymorphisms (SNPs) is critical for personalized clinical diagnosis, treatment, and medication. Current clinical detection methods suffer from primer dimerization and require the redesigning of reaction systems for different targets, resulting in a time-consuming and laborious process. Here, we present a robust and versatile method for SNP typing by using tailed primers and...
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