Article
Examination of disease-based selection, demographic history and population structure in European Y-chromosome haplogroup I.
Journal of human genetics - 1 Sept 2010
Sezgin Efe, Drosdak Alyssa, McIntosh Carl, Kessing Bailey, Lautenberger James A, Goedert James J, Phair John P, Troyer Jennifer L, Smith Michael W, O'Brien Stephen J
Abstract excerpt
We attempted to refine the understanding of an association of Y-chromosomal haplogroup I (hg-I) with enhanced AIDS progression that had been previously reported. First, we compared the progression phenotype between hg-I and its phylogenetically closest haplogroup J. Then, we took a candidate gene approach resequencing DDX3Y, a crucial autoimmunity gene, in hg-I and other common European Y-chromosome haplogroups...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.