Article
Association of Y chromosome haplogroup I with HIV progression, and HAART outcome.
Human genetics - 1 Apr 2009
Sezgin Efe, Lind Joanne M, Shrestha Sadeep, Hendrickson Sher, Goedert James J, Donfield Sharyne, Kirk Gregory D, Phair John P, Troyer Jennifer L, O'Brien Stephen J, Smith Michael W
Abstract excerpt
The host genetic basis of differential outcomes in HIV infection, progression, viral load set point and highly active retroviral therapy (HAART) responses was examined for the common Y haplogroups in European Americans and African Americans. Accelerated progression to acquired immune deficiency syndrome (AIDS) and related death in European Americans among Y chromosome haplogroup I (Y-I) subjects was discovered....
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