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Article

Population genetics-informed meta-analysis in seven genes associated with risk to dengue fever disease.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Aug 2018

Oliveira Marisa, Saraiva Diana P, Cavadas Bruno, Fernandes Verónica, Pedro Nicole, Casademont Isabelle, Koeth Fanny, Alshamali Farida, Harich Nourdin, Cherni Lotfi, Sierra Beatriz, Guzman Maria G, Sakuntabhai Anavaj, Pereira Luisa

Abstract excerpt

Population genetics theory predicted that rare frequent markers would be the main contributors for heritability of complex diseases, but meta-analyses of genome-wide association studies are revealing otherwise common markers, present in all population groups, as the identified candidate genes. In this work, we applied a population-genetics informed meta-analysis to 10 markers located in seven genes said to be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29673983
DOI: 10.1016/j.meegid.2018.04.018

Genes

MICB
OAS3
PLCE1
OAS1

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