Article
Cortical thickness is associated with different apolipoprotein E genotypes in healthy elderly adults.
Neuroscience letters - 2 Aug 2010
Fan Ming, Liu Bing, Zhou Yuan, Zhen Xiantong, Xu Cunlu, Jiang Tianzi
Abstract excerpt
Previous studies have consistently suggested that the varepsilon4 allele of apolipoprotein E (APOE) gene is a major risk factor for Alzheimer's disease (AD). However, whether the varepsilon2 allele, a possible protective factor for AD, will express its protective effect in terms of cortical thickness in healthy elderly carriers is unclear. The goal of this study is to clarify the effects of APOE genotypes on...
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