Article
Altered dynamics of intestinal cell maturation in Apc1638N/+ mice.
Cancer research - 1 Jul 2010
Wang Donghai, Pezo Rossanna C, Corner Georgia, Sison Cristina, Lesser Martin L, Shenoy Shailesh M, Mariadason John M, Singer Robert H, Augenlicht Leonard H
Abstract excerpt
Novel imaging of active transcription sites in interphase nuclei of intestinal epithelial cells in situ showed that key genes associated with Wnt and Notch signaling were dynamically regulated as the cells underwent normal maturation during their migration along the mouse crypt-villus axis (CVA)....
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