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Preliminary evidence that polymorphisms in dopamine-related transcription factors LMX1A, LMX1B and PITX3 are associated with schizophrenia.

Progress in neuro-psychopharmacology & biological psychiatry - 16 Aug 2010

Bergman Olle, Westberg Lars, Nilsson Lars-Göran, Adolfsson Rolf, Eriksson Elias

Abstract excerpt

The early development of dopaminergic pathways has been attributed importance for the aetiology of schizophrenia. Several transcription factors are involved in the survival and maturation of dopamine neurons, including LMX1A, LMX1B and PITX3. The possibility that polymorphisms in these genes may influence the development and/or the maintenance of dopaminergic neurons prompted us to investigate if five single...

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Source

Identifiers

PMID: 20570600
DOI: 10.1016/j.pnpbp.2010.05.032

Genes

PITX3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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