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Article

Association between PNPO and schizophrenia in the Japanese population.

Schizophrenia research - 1 Dec 2007

Song Hongwei, Ueno Shu-ichi, Numata Shusuke, Iga Jun-ichi, Shibuya-Tayoshi Sumiko, Nakataki Masahito, Tayoshi Shin'Ya, Yamauchi Ken, Sumitani Satsuki, Tomotake Tomohito, Tada Tomohito, Tanahashi Toshihito, Itakura Mitsuo, Ohmori Tetsuro

Abstract excerpt

Accumulating evidence suggests that both homocysteine metabolism and monoaminergic neurotransmitter systems are important in schizophrenia pathology. We hypothesized that the gene PNPO (pyridoxine 5'-phosphatase oxidase gene) might be a candidate for susceptibility to schizophrenia because PNPO encodes pyridoxamine 5'-phosphate oxidase (EC 1.4.3.5), a rate-limiting enzyme in pyridoxal 5'-phosphate (PLP, vitamin...

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Identifiers

PMID: 17851041
DOI: 10.1016/j.schres.2007.08.004

Genes

PNPO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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