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Article

Do polymorphisms in transcription factors LMX1A and LMX1B influence the risk for Parkinson's disease?

Journal of neural transmission (Vienna, Austria : 1996) - 1 Mar 2009

Bergman Olle, Håkansson Anna, Westberg Lars, Belin Andrea Carmine, Sydow Olof, Olson Lars, Holmberg Björn, Fratiglioni Laura, Bäckman Lars, Eriksson Elias, Nissbrandt Hans

Abstract excerpt

The key symptoms of Parkinson's disease (PD) are caused by degeneration of dopamine neurons originating in substantia nigra. Whereas, transcription factor LMX1A is crucial for the differentiation of mesencephalic dopamine neurons, LMX1B appears to be important for both the development and the survival of these cells. The aim of this study was to investigate if genetic variation in LMX1A and LMX1B differs between...

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PMID: 19189040
DOI: 10.1007/s00702-009-0187-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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