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Article

Genetic association analyses of PHOX2B and ASCL1 in neuropsychiatric disorders: evidence for association of ASCL1 with Parkinson's disease.

Human genetics - 1 Oct 2005

Ide Masayuki, Yamada Kazuo, Toyota Tomoko, Iwayama Yoshimi, Ishitsuka Yuichi, Minabe Yoshio, Nakamura Kazuhiko, Hattori Nobutaka, Asada Takashi, Mizuno Yoshikuni, Mori Norio, Yoshikawa Takeo

Abstract excerpt

We previously identified frequent deletion/insertion polymorphisms in the 20-alanine homopolymer stretch of PHOX2B (PMX2B), the gene for a transcription factor that plays important roles in the development of oculomotor nerves and catecholaminergic neurons and regulates the expression of both tyrosine hydroxylase and dopamine beta-hydroxylase genes. An association was detected between gene polymorphisms and...

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Source

Identifiers

PMID: 16021468
DOI: 10.1007/s00439-005-1342-8

Genes

ASCL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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