Article
Detection of SNP-SNP interactions in trios of parents with schizophrenic children.
Genetic epidemiology - 1 Jul 2010
Li Qing, Fallin M Daniele, Louis Thomas A, Lasseter Virginia K, McGrath John A, Avramopoulos Dimitri, Wolyniec Paula S, Valle David, Liang Kung-Yee, Pulver Ann E, Ruczinski Ingo
Abstract excerpt
Schizophrenia (SZ) is a heritable and complex psychiatric disorder with an estimated worldwide prevalence of about 1%. Research on the risk factors for SZ has thus far yielded few clues to causes, but has pointed to a heterogeneous etiology that likely involves multiple genes and gene-environment interactions. In this manuscript, we apply a novel method (trio logic regression, Li et al., 2009) to case-parent trio...
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