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Article

Common variants in genes that mediate immunity and risk of multiple myeloma.

International journal of cancer - 15 Jun 2007

Brown Elizabeth E, Lan Qing, Zheng Tongzhang, Zhang Yawei, Wang Sophia S, Hoar-Zahm Shelia, Chanock Stephen J, Rothman Nathaniel, Baris Dalsu

Abstract excerpt

Multiple myeloma (MM) is a B-cell malignancy characterized by aberrant immune function. Using genomic DNA extracted from 127 MM cases aged 21-84 years and 545 population-based controls, we examined the risk of MM associated with 82 common variants in 45 genes that mediate immunity among women of European American descent. Genotyping was determined using validated and optimized TaqMan assays. We estimated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17315188
DOI: 10.1002/ijc.22618

Genes

LTA
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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