Article
Association of the RAGE G82S polymorphism with Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jul 2010
Daborg Jonny, von Otter Malin, Sjölander Annica, Nilsson Staffan, Minthon Lennart, Gustafson Deborah R, Skoog Ingmar, Blennow Kaj, Zetterberg Henrik
Abstract excerpt
The receptor for advanced glycation end-products (RAGE) has been implicated in several pathophysiological processes relevant to Alzheimer's disease (AD), including transport and synaptotoxicity of AD-associated amyloid beta (Abeta) peptides. A recent Chinese study (Li et al. in J Neural Transm 117:97-104, 2010) suggested an association between the 82S allele of the functional single nucleotide polymorphism (SNP)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
