Article
Polymorphisms in the receptor for advanced glycation end products gene are associated with susceptibility to drug-resistant epilepsy.
Neuroscience letters - 21 Apr 2016
Guo Mingxing, Wang Jiafeng, Qi Huili, Liu Fei, Yao Lifen, Zhang Shuyan, Li Keshen
Abstract excerpt
Increasing evidence has demonstrated that inflammation plays an important role in epilepsy (EP). As a cell-surface molecule of the immunoglobulin superfamily, the receptor for advanced glycation end products (RAGE) is involved in inflammation-related disease. Functional polymorphisms in the regulatory elements and/or ligand-binding regions of RAGE may alter the expression and function of RAGE, thus affecting EP...
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