Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RAGE and AGEs in Mild Cognitive Impairment of Diabetic Patients: A Cross-Sectional Study.

PloS one - 1 Jan 2016

Wang Pin, Huang Rong, Lu Sen, Xia Wenqing, Cai Rongrong, Sun Haixia, Wang Shaohua

Abstract excerpt

OBJECTIVE: Receptor for advanced glycation end products (AGEs; RAGE) binds to both AGEs and amyloid-beta peptides. RAGE is involved in chronic complications of type 2 diabetes and Alzheimer's disease. We aimed to investigate the roles of RAGE, AGEs and the Gly82Ser polymorphism of RAGE in mild cognitive impairment (MCI) among type 2 diabetes patients. METHODS: Of the 167 hospitalized type 2 diabetes patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cognitive Dysfunction
Share to Cross-Sectional Studies
Share to Demography

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glycation End Products, Advanced

Share to Logistic Models

Share to Neuropsychological Tests

Share to Receptor for Advanced Glycation End Products

Source

Open in PubMed Open full text

Identifiers

PMID: 26745632
DOI: 10.1371/journal.pone.0145521
PMCID: PMC4706319

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RAGE and AGEs in Mild Cognitive Impairment of Diabetic Patients: A Cross-Sectional Study.PMID 26745632Read ↗

Multifactorial Therapeutic Strategies Targeting Advanced Glycation End-Products, Oxidative Stress, and Metabolic Dysfunction in Alzheimer's DiseaseSemantic proximity Read ↗

RAGE: The Beneficial and Deleterious Effects by Diverse Mechanisms of ActionsSemantic proximity Read ↗

Genetic association between RAGE polymorphisms and Alzheimer's disease and Lewy body dementias in a Japanese cohort: a case-control study.Semantic proximity Read ↗

Association between the RAGE G82S polymorphism and Alzheimer's disease.Semantic proximity Read ↗

Association of the RAGE G82S polymorphism with Alzheimer's disease.Semantic proximity Read ↗

APOE ε4 Carriers Have a Greater Propensity to Glycation and sRAGE Which Is Further Influenced by RAGE G82S Polymorphism.Semantic proximity Read ↗

A combination of midlife diabetes mellitus and the apolipoprotein E ε4 allele increase risk for cognitive declineSemantic proximity Read ↗

RAGE: A Multi-Ligand Receptor Unveiling Novel Insights in Health and DiseaseSemantic proximity Read ↗

Association of the receptor for advanced glycation end products gene polymorphisms and circulating RAGE levels with diabetic retinopathy in the Chinese population.Semantic proximity Read ↗

Cognitive impairment: an increasingly important complication of type 2 diabetes: the age, gene/environment susceptibility--Reykjavik study.Semantic proximity Read ↗

Receptor for age (RAGE) is a gene within the major histocompatibility class III region: implications for host response mechanisms in homeostasis and chronic diseaseSemantic proximity Read ↗

Soluble receptor for AGE (RAGE) is a novel independent predictor of all-cause and cardiovascular mortality in type 1 diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.