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Article

Targeted disruption of pancreatic-derived factor (PANDER, FAM3B) impairs pancreatic beta-cell function.

Diabetes - 1 Sept 2010

Robert-Cooperman Claudia E, Carnegie Jason R, Wilson Camella G, Yang Jichun, Cook Joshua R, Wu Jianmei, Young Robert A, Wolf Bryan A, Burkhardt Brant R

Abstract excerpt

OBJECTIVE: Pancreatic-derived factor (PANDER, FAM3B) is a pancreatic islet-specific cytokine-like protein that is secreted from beta-cells upon glucose stimulation. The biological function of PANDER is unknown, and to address this we generated and characterized a PANDER knockout mouse. RESEARCH D...

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Identifiers

PMID: 20566664
DOI: 10.2337/db09-1552
PMCID: PMC2927943

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20566664-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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