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Article

Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells.

Gastroenterology - 1 Jul 2010

Masui Toshihiko, Swift Galvin H, Deering Tye, Shen Chengcheng, Coats Ward S, Long Qiaoming, Elsässer Hans-Peter, Magnuson Mark A, MacDonald Raymond J

Abstract excerpt

BACKGROUND & AIMS: The mature pancreatic acinar cell is dedicated to the production of very large amounts of digestive enzymes. The early stages of pancreatic development require the Rbpj form of the trimeric Pancreas Transcription Factor 1 complex (PTF1-J). As acinar development commences, Rbpjl gradually replaces Rbpj; in the mature pancreas, PTF1 contains Rbpjl (PTF1-L). We investigated whether PTF1-L controls...

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Identifiers

PMID: 20398665
DOI: 10.1053/j.gastro.2010.04.003
PMCID: PMC2902682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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