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Article

Thymic stromal lymphopoietin (TSLP) is associated with allergic rhinitis in children with asthma

18 Jan 2011

Abstract excerpt

BACKGROUND: Allergic rhinitis (AR) affects up to 80% of children with asthma and increases asthma severity. Thymic stromal lymphopoietin (TSLP) is a key mediator of allergic inflammation. The role of the TSLP gene (TSLP) in the pathogenesis of AR has not been studied. OBJECTIVE: To test for associations between variants in TSLP, TSLP-related genes, and AR in children with asthma. METHODS: We genotyped 15 single...

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PMID: 21244681
DOI: 10.1186/1476-7961-9-1

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