Article
Sex-stratified linkage analysis identifies a female-specific locus for IgE to cockroach in Costa Ricans.
American journal of respiratory and critical care medicine - 15 Apr 2008
Hunninghake Gary M, Lasky-Su Jessica, Soto-Quirós Manuel E, Avila Lydiana, Liang Catherine, Lake Stephen L, Hudson Thomas J, Spesny Mitzi, Fournier Eduardo, Sylvia Jody S, Freimer Nelson B, Klanderman Barbara J, Raby Benjamin A, Celedón Juan C
Abstract excerpt
RATIONALE: The basis for gender influences on allergen-specific IgEs is unclear. OBJECTIVES: To perform regular and sex-stratified genomewide linkage analyses of IgE to each of three allergens (Ascaris lumbricoides, Blatella germanica [German cockroach]), and Dermatophagoides pteronyssinus [dust mite]) and to conduct an association study of a candidate gene in a linked genomic region. METHODS: Genomewide linkage...
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