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Article

Genetic variation in the retinoid X receptor and calcium-sensing receptor and risk of colorectal cancer in the Colon Cancer Family Registry.

Carcinogenesis - 1 Aug 2010

Jacobs Elizabeth T, Martínez Maria E, Campbell Peter T, Conti David V, Duggan David, Figueiredo Jane C, Haile Robert W, LeRoy Elizabeth C, Poynter Jenny N, Thompson Patricia A, Baron John A

Abstract excerpt

Genetic variants in the calcium/vitamin D metabolic pathway may be related to risk for colorectal cancer. While several investigations of vitamin D receptor (VDR) polymorphisms and colorectal cancer have been conducted, no studies to date have evaluated the association of genetic variation in the heterodimer partner for VDR, the retinoid X receptor (RXR). Another important gene in this pathway is the...

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Identifiers

PMID: 20558521
DOI: 10.1093/carcin/bgq127
PMCID: PMC2915636

Genes

CASR
RXRA
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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