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Article

Calcium, vitamin D, VDR genotypes, and epigenetic and genetic changes in rectal tumors.

Nutrition and cancer - 1 Jan 2010

Slattery Martha L, Wolff Roger K, Herrick Jennifer S, Caan Bette J, Samowitz Wade

Abstract excerpt

Calcium, vitamin D, exposure to sunshine, and vitamin D receptor (VDR) genotypes have been associated rectal cancer. We used data from 750 rectal tumors and 1,205 population-based controls examine associations with TP53, KRAS2, and CpG Island methylator phenotype (CIMP) markers. Rectal tumors were associated with high levels of calcium overall and with TP53 tumor mutations specifically (OR = 0.6, 95% CI =...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20432164
DOI: 10.1080/01635580903441204
PMCID: PMC2895459

Genes

VDR
CDX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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