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Article

Activation of brain endothelium by pneumococcal neuraminidase NanA promotes bacterial internalization.

Cellular microbiology - 1 Nov 2010

Banerjee Anirban, Van Sorge Nina M, Sheen Tamsin R, Uchiyama Satoshi, Mitchell Tim J, Doran Kelly S

Abstract excerpt

Streptococcus pneumoniae (SPN), the leading cause of meningitis in children and adults worldwide, is associated with an overwhelming host inflammatory response and subsequent brain injury. Here we examine the global response of the blood-brain barrier to SPN infection and the role of neuraminidas...

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Source

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Identifiers

PMID: 20557315
DOI: 10.1111/j.1462-5822.2010.01490.x
PMCID: PMC2943548

Genes

SPN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20557315-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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