Article
Pneumococcal neuraminidase A: an essential upper airway colonization factor for Streptococcus pneumoniae.
Molecular oral microbiology - 1 Aug 2012
Brittan J L, Buckeridge T J, Finn A, Kadioglu A, Jenkinson H F
Abstract excerpt
Streptococcus pneumoniae colonizes the upper respiratory tract from where the organisms may disseminate systemically to cause life threatening infections. The mechanisms by which pneumococci colonize epithelia are not understood, but neuraminidase A (NanA) has a major role in promoting growth and survival in the upper respiratory tract. In this article we show that mutants of S. pneumoniae D39 deficient in NanA...
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