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Article

Dual roles for the Mss116 cofactor during splicing of the ai5γ group II intron.

Nucleic acids research - 1 Oct 2010

Zingler Nora, Solem Amanda, Pyle Anna Marie

Abstract excerpt

The autocatalytic group II intron ai5γ from Saccharomyces cerevisiae self-splices under high-salt conditions in vitro, but requires the assistance of the DEAD-box protein Mss116 in vivo and under near-physiological conditions in vitro. Here, we show that Mss116 influences the folding mechanism in several ways. By comparing intron precursor RNAs with long (∼300 nt) and short (∼20 nt) exons, we observe that long...

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Identifiers

PMID: 20554854
DOI: 10.1093/nar/gkq530
PMCID: PMC2965245

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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