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Article

A DEAD-box protein functions as an ATP-dependent RNA chaperone in group I intron splicing.

Cell - 14 Jun 2002

Mohr Sabine, Stryker John M, Lambowitz Alan M

Abstract excerpt

The Neurospora crassa CYT-18 protein, the mitochondrial tyrosyl-tRNA synthetase, functions in splicing group I introns by inducing formation of the catalytically active RNA structure. Here, we identified a DEAD-box protein (CYT-19) that functions in concert with CYT-18 to promote group I intron splicing in vivo and vitro. CYT-19 does not bind specifically to group I intron RNAs and instead functions as an...

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Identifiers

PMID: 12086675
DOI: 10.1016/s0092-8674(02)00771-7

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A DEAD-box protein functions as an ATP-dependent RNA chaperone in group I intron splicing.PMID 12086675Read ↗

The splicing of yeast mitochondrial group I and group II introns requires a DEAD-box protein with RNA chaperone function.Semantic proximity Read ↗

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