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Article

Resequencing of the vascular endothelial growth factor promoter reveals haplotype structure and functional diversity.

Angiogenesis - 1 Sept 2010

Radovich Milan, Hancock Bradley A, Kassem Nawal, Mi Deming, Skaar Todd C, Schneider Bryan P

Abstract excerpt

Our group has previously reported that SNPs in the VEGF promoter are strongly associated with efficacy and toxicity to the anti-VEGF antibody bevacizumab in breast cancer. In order to better understand the biologic mechanism for our previously reported biomarkers, we embarked on a comprehensive evaluation of genetic variation in the VEGF promoter coupled with a study of its intrinsic function. We resequenced 48...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 20552269
DOI: 10.1007/s10456-010-9173-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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