Article
Strain-dependent variation in collateral circulatory function in mouse hindlimb.
Physiological genomics - 1 Aug 2010
Chalothorn Dan, Faber James E
Abstract excerpt
The extent (density and diameter) of the native (preexisting) collateral circulation in healthy tissues and the capacity of collaterals to enlarge/remodel in obstructive arterial disease are important determinants of ischemic injury. Evidence suggests that these parameters vary widely from yet-to-be-identified genetic and environmental factors. Recently, a locus on chromosome 7 was linked to less recovery of...
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