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Article

Wide genetic variation in the native pial collateral circulation is a major determinant of variation in severity of stroke.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 May 2010

Zhang Hua, Prabhakar Pranay, Sealock Robert, Faber James E

Abstract excerpt

Severity of stroke varies widely among individuals. Whether differences in the extent of the native (preexisting) pial collateral circulation exist and contribute to this variability is unknown. We addressed these questions and probed for potential genetic contributions using morphometric analysis of the collateral circulation in 15 inbred mouse strains recently shown to exhibit wide differences in infarct...

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Source

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Identifiers

PMID: 20125182
DOI: 10.1038/jcbfm.2010.10
PMCID: PMC2949178

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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