Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic dissection of the Canq1 locus governing variation in extent of the collateral circulation.

PloS one - 1 Jan 2012

Wang Shiliang, Zhang Hua, Wiltshire Tim, Sealock Robert, Faber James E

Abstract excerpt

BACKGROUND: Native (pre-existing) collaterals are arteriole-to-arteriole anastomoses that interconnect adjacent arterial trees and serve as endogenous bypass vessels that limit tissue injury in ischemic stroke, myocardial infarction, coronary and peripheral artery disease. Their extent (number and diameter) varies widely among mouse strains and healthy humans. We previously identified a major quantitative trait...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Mammalian
Share to Cluster Analysis
Share to Gene Expression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to Hemostasis

Share to Mice, Inbred BALB C

Share to Mice, Knockout

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 22412848
DOI: 10.1371/journal.pone.0031910
PMCID: PMC3295810

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic dissection of the Canq1 locus governing variation in extent of the collateral circulation.PMID 22412848Read ↗

Large differences in collateral blood vessel abundance among individuals arise from multiple genetic variantsSemantic proximity Read ↗

Genetic architecture underlying variation in extent and remodeling of the collateral circulation.Semantic proximity Read ↗

A novel genetic locus modulates infarct volume independently of the extent of collateral circulation.Semantic proximity Read ↗

Natural genetic variation of integrin alpha L (Itgal) modulates ischemic brain injury in stroke.Semantic proximity Read ↗

Wide genetic variation in the native pial collateral circulation is a major determinant of variation in severity of stroke.Semantic proximity Read ↗

Genetic variation in retinal vascular patterning predicts variation in pial collateral extent and stroke severity.Semantic proximity Read ↗

Strain-dependent variation in collateral circulatory function in mouse hindlimb.Semantic proximity Read ↗

A neuroprotective locus modulates ischemic stroke infarction independent of collateral vessel anatomySemantic proximity Read ↗

Identification of novel neuroprotective loci modulating ischemic stroke volume in a cross between wild-derived inbred mouse strainsSemantic proximity Read ↗

Role of Genetic Variation in Collateral Circulation in the Evolution of Acute Stroke: A Multimodal Magnetic Resonance Imaging Study.Semantic proximity Read ↗

Genetic and Environmental Contributions to Variation in the Posterior Communicating Collaterals of the Circle of Willis.Semantic proximity Read ↗

<i>Ide</i> copy number variant does not influence lesion size and mortality in two C57BL/6J mouse models of cerebrovascular ischemia nor in human cerebrovascular disease. An exploratory studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.